Marijuana In Detail.

Marijuana In Detail Marijuana causes long-term changes in the foreland similar to those seen with other drugs of abuse . . . Back in the 1970s, zoology experiments led to groundless fears that marijuana blew holes in brain tissue. The experiments organisations ilk NIDA now fund be more sophisticated only when the controversy still rages. George Koob, an addiction researcher from The Scripps Research

Institute in La Jolla, California, claims the new message from the animals is simple: The more we discover roughly the neurobiology of addiction the more common elements were seeing between tetrahydrocannabinol (tetrahydrocannabinol, the main active ingredient in cannabis) and other drugs of abuse. And for Koob, one of these newly discovered common elements is marijaunas ability to trigger chemical substance changes in the brain that lead to strong onanism symptoms.

In humans, rough researchers claim to see clear evidence of insomnia, anxiety and still flu-like symptoms in heavy cannabis users who abstain. But if theres a consensus, its that symptoms are mild and variable. By contrast, Koobs rats are shivering wrecks. Does this mean marijuana is more addictive than we think?

Not a bit of it, says Roger Pertwee, a university pharmacologist and president of the Cannabinoid Research Society. Thats because those symptoms arent so much observed as manufactured. The animals are injected with high doses of THC, then injected with a moment chemical to block cannabis receptors in the brain.

Without the block, the sharp withdrawal symptoms cant be seen because cannabis clears so slowly that even to a great extent doped rats are likely to experience a quench wind down. Another debate rages over animal studies into the short effects of marijuana on brain chemistry. Heroin, cocaine, alcohol and nicotine tout ensemble trigger a surge in the chemical dopamine in a small midbrain structure called the core accumbens. Many researchers...

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